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In a rat model of IBS established by acetic acid irrigation combined with chronic acute stress, VNS improved depressive behavior, abnormal fecal output, and excessive abdominal withdrawal reflex in IBS rats, the mechanism of which may be related to 7nAChR reducing levels of inflammatory cytokines (19)

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The BPC-157 + TB-500 blend is a 1:1 formulation at standard research doses

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2014, Apr;94(2):35582